Basophil Activation Test Based on CD203c Expression in the Diagnosis of Fish Allergy
نویسندگان
چکیده
منابع مشابه
Basophil activation test based on the expression of CD203c in the diagnostics of cow milk allergy in children
BACKGROUND Detection of allergen-induced basophil activation by flow cytometry has been shown to be a useful tool for allergy diagnosis. OBJECTIVE The aim of this study was to assess the potential of this technique for the diagnosis of pediatric cow milk allergy. MATERIAL AND METHODS The quantification of total and specific IgE and basophil activation test were performed to evaluate cow mil...
متن کاملComparison of two basophil activation markers CD63 and CD203c in the diagnosis of amoxicillin allergy.
BACKGROUND To confirm allergy to beta-lactam (BL), a basophil activation test in flow cytometry based on CD63 up-regulation was described. CD203c is a more recent basophil activation marker and up to day there is no consensus about which marker is the more sensitive one. CD203c has not yet been evaluated in the diagnosis of BL allergy. OBJECTIVE The aim of the study was to compare the reliabi...
متن کامل[Basophil activation test in the diagnosis of allergy to medicines].
In this paper we study the reliability of the basophil activation test (BAT) in the "in-vitro" diagnosis of allergy to betalactams and to metamizol, and the sensitivity and specificity of the technique are analyzed. To this end, we studied 58 patients allergic to betalactam antibiotics with a positive cutaneous test facing any derivative of penicillin and 30 healthy controls who tolerated betal...
متن کاملIs basophil activation test (BAT) really useful for allergy diagnosis?
Dear Editor, both the paper by Pereira Santos et al and the Editorial on the latest issue of this Journal, stressed on the essential, fairly irreplaceable role of basophil activation test (BAT) in allergy diagnosis (1,2). Certainly, BAT is a cell-based test and in this sense it should give fundamental insights about the role of these circulating leukocytes in hypersensitivity reactions, chronic...
متن کاملExpression of Basophil Activation Markers in Pediatric Asthma
Background: Asthma is very common in children and its diagnosis is based on clinical manifestations, which can be misdiagnosed as other respiratory diseases with similar signs and symptoms. Objective: To analyze the expression of ST2L and CD203c in the diagnosis of pediatric asthma. Methods: Basophils were purified from whole blood samples of patients and healthy controls using Ficol-Paque grad...
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ژورنال
عنوان ژورنال: Allergy, Asthma & Immunology Research
سال: 2020
ISSN: 2092-7355,2092-7363
DOI: 10.4168/aair.2020.12.4.641